Hybrid Odontogenic Tumor with a unique presentation of the Calcifying Epithelial Odontogenic Tumor, Adenomatoid Odontogenic Tumor, and Calcifying Odontogenic Cyst: A Case Report

There are rarely hybrid neoplasms composed of two or more distinct histological types; a hybrid odontogenic tumor with a combination of the calcifying epithelial odontogenic tumor (CEOT) is present, adenomatoid odontogenic tumor (AOT) and calcifying odontogenic cyst (COC), located in the anterior mandible region from a 15-year-old male patient causing mild mobility of anterior mandible incisors with the labial and lingual expansion of the mandible cortical plates and obvious facial asymmetry. The tumor was surgically removed through an en-bloc resection approach. Microscopic examination revealed an atypical hybrid odontogenic tumor, with features of the three entities previously mentioned. Several cases of hybrid neoplasms have been reported in the literature. However, there is no evidence about the incidence of a hybrid odontogenic tumor with histologic features of CEOT combined with two other entities. In combination with COC, this is a unique presentation of a hybrid tumor not previously documented.